David Watt

Professor of Chemistry
Associate Dean, College of Medicine

Organic Chemistry

Office: Mn144 Medical Science Building 0298
Phone: (606) 323-6589
FAX: (606) 323-2039
email: dwatt@pop.uky.edu

Education

Selected Publications

M. Golinski, S. Vasudevan, R. Floresca, C. P. Brock and D. S. Watt, "An Enantioselective Approach to Ring A of Taxol Using the Wieland-Miescher Ketone," Tetrahedron Lett., 34, 55-58 (1993).

M. Golinski, C. P. Brock and D. S. Watt, "Addition of tert-Butyldimethyl- or tert- Butyldiphenylsilyl Cyanide to Hindered Ketones," J. Org. Chem., 58, 159-164 (1993).

R. Floresca, M. Kurihara, D. S. Watt and A. Demir, "Cleavage of Unsaturated a-Ketols to w-Oxo-a,b-unsaturated Acids," J. Org. Chem., 58, 2196-2200 (1993).

I. Stoilov, E. Kolaczkowska, D. S. Watt, J. St. Pyrek, R. M. K. Carlson, F. J. Fago and J. M. Moldowan, "Synthesis of Biological Markers in Fossil Fuels 7. Selected Diastereomers of 4a-Methyl-5a-stigmastane and 5a-Dinosterane," J. Org. Chem., 58, 3444-3454 (1993).

K. Rajagopalan, A. J. Chavan, B. E. Haley and D. S. Watt, "Synthesis and Application of Bidentate Photoaffinity Cross-Linking Reagents: Nucleotide Photoaffinity Probes with Two Photoactive Groups," J. Biol. Chem., 268, 14230-14238 (1993).

M. E. Salvucci, K. Rajagopalan, G. Sievert, B. E. Haley and D. S. Watt, "Photoaffinity Labeling of Rubisco Activase with ATP-Benzophenone: Identification of the ATP g- Phosphate Binding Domain," J. Biol. Chem., 268, 14239-14244 (1993).

A. J. Chavan, S. K. Richardson, H. Kim, B. E. Haley and D. S. Watt, "Forskolin Photoaffinity Probes for the Evaluation of Tubulin Binding Sites," Bioconjugate Chem., 4, 268-274 (1993).

I. Stoilov, D. S. Watt, J. P. Goodman and J. St. Pyrek, "Synthesis of Detomidine and Medetomidine Metabolites:1,2,3-Trisubstituted Arenes with 4 (5 )-Imidazolylmethyl Groups," J. Heterocyclic Chem., 30, 1645-1651 (1993).

S. Vasudevan and D. S. Watt, "Hydrolysis of 1,4,6-Trioxaspiro[4.5]decanes to d-Lactones Using 2,3-Dichloro-5,6-dicyanobenzoquinone in Aqueous Acetone," J. Org. Chem., 59, 361-364 (1994).

M. A. McCaffrey, J. M. Moldowan, P. A. Lipton, R. E. Summons, K. E. Peters, A. Jeganathan and D. S. Watt, "Paleoenvironmental Implications of Novel C30 Steranes in Precambrian to Cenozoic Age Petroleum and Bitumen," Geochim. Cosmochim. Acta, 58, 529-532 (1994).

C. P. Brock, S. K. Richardson, M. R. Sabol, D. S. Watt and A. Syed, "An Octahydro-3a,6-methanoazulen-5-one Resulting from an Intramolecular Friedel-Crafts Acylation," Acta Cryst., C50, 106-108 (1994).

S. Stanley, T. Wood, J. P. Goodman, P. Henry, W. E. Woods, S. L. Chang, H.-H. Tai, D. Watt, S. Kwiatkowski, J. W. Blake, T. Tobin, D. Gerken and R. Sams, "Immunoassay Detection of Drugs in Racing Horses: Detection of Ethacrynic Acid and Bumetanide in Equine Blood and Urine by ELISA," J. Anal. Tox., 18, 95-100 (1994).

I. Stoilov, S. L. Smith, D. S. Watt, R. M. K. Carlson, F. J. Fago and J. M. Moldowan, "1H and 13C NMR Analysis of C-23 and C-24 Diastereomers of 5a-Dinosterane," Mag. Res. Chem., 32, 101-106 (1994).

I. Stoilov, R. Shetty, J. St. Pyrek, S. L. Smith, W. J. Layton, D. S. Watt, R. M. K. Carlson and J. M. Moldowan, "A Synthesis of a Triaromatic Steroid Biomarker, (20R,24R)-4,17b-Dimethyl-18,19-dinorstigmasta-1,3,5,7,9,11,13-heptaene, from Stigmasterol," J. Org. Chem., 59, 926-928 (1994).

C. P. Brock, I. Stoilov and D. S. Watt, "A Steroid Derivative that Crystallizes with Three Molecules in the Asymmetric Unit," Acta Cryst., C50, 434-438 (1994).

A. Marcinek, M. S. Platz, S. Y. Chan, R. Floresca, K. Rajagopalan, M. Golinski and D. S. Watt, "Unusually Long Lifetimes of the Singlet Nitrenes Derived from 4-Azido-2,3,5,6-tetrafluorobenzamides," J. Phys. Chem., 98, 412-419 (1994).

This document and associated figures are copyright 1995-1997 by David S. Watt. All rights reserved.